Last edited by Doular
Friday, May 15, 2020 | History

2 edition of Chemical-induced erythrocytosis in wistar rats found in the catalog.

Chemical-induced erythrocytosis in wistar rats

Gerry Michael Henningsen

Chemical-induced erythrocytosis in wistar rats

assessment as a model for human polycythemia

by Gerry Michael Henningsen

  • 325 Want to read
  • 3 Currently reading

Published .
Written in English

    Subjects:
  • Erythrocyte disorders.,
  • Polycythemia.

  • Edition Notes

    Other titlesChemical induced erythrocytosis in wistar rats.
    Statementby Gerry Michael Henningsen.
    The Physical Object
    Paginationxi, 127 leaves, bound :
    Number of Pages127
    ID Numbers
    Open LibraryOL16971782M

    Secondary erythrocytosis develops as a result of a disorder that increases erythropoietin secretion. Erythropoietin is a hormone made in the kidneys that stimulates the bone marrow to produce red blood cells. As such, secondary erythrocytosis is not considered a myeloproliferative neoplasm. Absolute increase in HCT or RBC mass (erythrocytosis): This is due to increased erythropoiesis and can be primary (a bone marrow disorder) or secondary, due to appropriate or inappropriate production of the erythropoietic cytokine, erythropoietin. Primary erythrocytosis: This can .

    Westerman MP, Jenkins JL, Dekker A, et al. Significance of erythrocytosis and increased erythropoietin secretion after renal transplantation. Lancet. ;–7. PubMed CrossRef Google Scholar. Liver is a metabolically active organ responsible for many vital life functions. More than drugs, toxins, and herbs have been reported to cause liver injury. In spite of tremendous advances in modern medicine, there are hardly any reliable drugs that protect the liver from damage and/or help in regeneration of hepatic cell. It is, therefore, necessary to search for effective and safe Author: Khondakar Mahmudul Hasan, Samina Yesmin, Sarkar Farhana Akhter, Subrata Paul, Sabarni Sarker, Ariful.

    @article{osti_, title = {Comparisons of carcinogenicities of nickel compounds in rats}, author = {Sunderman, F.W. Jr. and Maenza, R.M.}, abstractNote = {This study demonstrates marked differences in the incidences of sarcomas in Fischer rats within 2 years after a single im injection of 4 insoluble nickel-containing powders amorphous nickel monosulfide (NiS), nickel subsulfide   comment: Cystic degeneration of the adrenal cortex (Figure 1, Figure 2, Figure 3, Figure 4, and Figure 5) occurs in many strains of rats but has apparently not been reported in nces vary with rat strain, with some strains (e.g., Sprague-Dawley, Wistar) exhibiting much higher incidences than others (e.g., F).


Share this book
You might also like
For heroism or extraordinary achievement while participating in aerial flight

For heroism or extraordinary achievement while participating in aerial flight

Prevalence estimates of alcohol and drug abuse for counties in Michigan.

Prevalence estimates of alcohol and drug abuse for counties in Michigan.

Interlibrary cooperation and the special libraries in Kuwait

Interlibrary cooperation and the special libraries in Kuwait

Critical perspectives on accounting and finance

Critical perspectives on accounting and finance

Aircraft Nose Art from World War I to Today

Aircraft Nose Art from World War I to Today

Peanut and Fifi have a ball

Peanut and Fifi have a ball

Rainbow in my heart

Rainbow in my heart

GLOBAL VACATION GROUP, INC.

GLOBAL VACATION GROUP, INC.

Malawi DHS EdData survey, 2002

Malawi DHS EdData survey, 2002

Hungarian literature in English translation published in Great Britain, 1830-1968

Hungarian literature in English translation published in Great Britain, 1830-1968

Schmidt-Dahler Family History

Schmidt-Dahler Family History

Standard reference materials

Standard reference materials

Contemporary moral problems

Contemporary moral problems

The story of Breadsall Church

The story of Breadsall Church

Chemical-induced erythrocytosis in wistar rats by Gerry Michael Henningsen Download PDF EPUB FB2

CHEMICAL-INDUCED ERYTHROCYTOSIS IN WISTAR RATS: ASSESSMENT AS A MODEL FOR HUMAN POLYCYTHEMIA Abstract by Gerry Michael Henningsen, DVM, PhD Washington State University May Chair: Loren D.

Koller Polycythemia is a hematological disease characterized by ery-throcytosis and occasionally leukocytosis. Many types of poly-Author: G M Henningsen. The erythropoietin titer was high in SH rats, and was undetectable in normotensive rats. These observations suggest a direct relationship between the hypertension and the erythrocytosis mediated by erythropoietin; both are genetically by:   Typically, induction of colitis using acetic acid involves anaesthetizing the rats with ether anteceded by a 24 h fast.

Subsequently, using a medical-grade polyurethane tube for enteral feeding (external diameter 2 mm), 1~2 ml of (3~4%) acetic acid is instilled 6~8 cm proximal to the anus by: It has been used for centuries in China to counteract alcohol intoxication.

However, the effects of puerarin on chemical-induced liver fibrosis have not been reported. In the present study, we investigated the effects of puerarin on liver fibrosis in Wistar rats induced by alcohol plus carbon tetrachloride by: Study conducted by Yang et al stated that recurrent ulcerative colitis model can also be induced in Wistar rats by instilling TNBS ( mg/kg) into the colon through an obtuse cannula.

This is followed by a second instillation with TNBS at a dose of mg/kg into the colon 14 days after the first induction of colitis leading to generation of.

Spontaneous rates of atrial thrombosis were determined for control Fischer rats and B6C3F1 mice: 0% in rats and mice in day studies and % in both genders of mice, 4% in male rats, and 1%.

Publisher Summary. The rat is the most widely recommended mammalian species in in vivo chemical safety studies in the international and Japanese national guidelines. Movements towards the harmonization of requirements for chemical safety studies in pharmaceuticals were started in among Japan, the EU, and the USA in the form of the international conference on harmonization.

Effect of J. regia extract and BLM on XO activity in lung tissue of rats. Values are expressed as means AE SE (n = 6). BLM caused a significant increase in XO activity in lung tissues when. In the study, NaPB was administered at various dietary levels for 7 days to male Wistar rats, CD-1 mice, and chimeric mice with human hepatocytes.

The treatment of chimeric mice with – ppm NaPB resulted in plasma PB levels around threefold to fivefold higher than those observed in human subjects given therapeutic doses of by: 2. The hepatotoxicity of thioacetamide (TA) has been known since In rats, single doses cause centrolobular necrosis accompanied by increases in plasma transaminases and bilirubin.

To elicit these effects, TA requires oxidative bioactivation, leading first to its S-oxide (TASO) and then to its chemically reactive S,S-dioxide (TASO2), which ultimately modifies amine-lipids and by: Wistar Institute in Philadelphia, giving rise to the ubiquitous present-day Wistar strain of rats (Festing, ).

The development of today's laboratory rat has been essentially an American initiative and the great majority of the strains of these animals that are presently in use throughout the scientific world have originated in the Size: KB.

The Wistar rat is currently one of the most popular rats used for laboratory research. It is characterized by its wide head, long ears, and a tail length that is always less than its body length.

The Sprague Dawley rat and Long–Evans rat were developed from Wistar rats. Wistar rats are more active than others like Sprague Dawley rats. In the present study we investigated the anti-amnesic activity of Vitex negundo in scopolamine induced amnesia in rats.

Wistar rats ( g) were trained on active avoidance task. Each animal received session of 15 trials with inter trial duration of 15 s for 5 days. Scopolamine (3 mg/kg, i.p) was administered at different time periods on the basis of stages of memory i.e acquisition.

Our earlier studies show MRN may protect against age-induced ROS in rats through modulation of protein oxidation, antioxidant status, and lipid peroxidation in the blood, liver, and brain tissues 7.

In this study, MRN also acts as a potent antioxidant agent in Cited by: 4. Results indicated that ingestion of CCl 4 in Wistar albino rats caused a significant (P rats with CBE resulted in a significant (P Cited by: 3.

In conclusion, the present study has shown that vitamin C pretreatment ameliorated the chronic CPF-induced hemotoxicity in Wistar rats. This may be partly due to free radical scavenging properties of the antioxidant vitamin, which attenuated CPF-evoked lipoperoxidation to the blood cellular by: Therefore, male Wistar rats were treated daily with mg/kg gentamicin or mg/kg gentamicin plus mg/kg ceftriaxone for 14 days i.p.

Serum biochemical parameters were measured on days. All of the samples are from the paraffin blocks of gastric tissues of Wistar rats that were entered in a study of gastric carcinogenesis induced by MNNG (M, Sigma) neonatally. Briefly, neonatal Wistar rats at 3 days of age were administrated ml of MNNG (8 μg/ml in water) per capita daily by gavage for ten days by: Round 1.

Reviewer 1 Report. The manuscript entitled 2Alleviating effect of alpha-lipoic acid and magnesium on cadmium-induced inflammatory processes, oxidative stress and bone metabolism disorders in Wistar rats” submitted to International Journal of Environmental Research and Public Health” by wics-Gorka and co-workers describes the effects on cadmium administration on.

Cadmium-induced Renopathy in Wistar Male Rats: Protection by Methanolic Leaf Extract of Momordica charantia Linn Article (PDF Available) in IOSR Journal of Pharmacy and Biological Sciences 4(3).

Both parameters in the Wistar Hannover GALAS rats were significantly lower than those in the Crl:CD(SD) rats. The mean of the dead embryo/fetus ratio during the gestation period was % in the Wistar Hannover GALAS rats and % in the Crl:CD(SD) rats, with Cited by: 7.

Forty-eight male Wistar rats were randomly divided into eight groups: normoxia control, hypoxia control, hypoxia + acetazolamide (30 mgkg −1 d −1), and five hypoxia + methazolamide groups (5, 10, 30, 90, and mgkg −1 d −1).

Excessive erythrocytosis was induced through 4 weeks of hypobaric hypoxia (8 hours O 2 10%/16 hours O 2 Cited by: 1.Protective effects of Moringa oleifera Lam. on cadmium-induced liver and kidney damage in male Wistar rats.

Male adult Wistar rats treated with cadmium ( mg/kg body wt, five times a week.